产品货号：
Z36675
中文名称：
RNF4抗体
英文名称：
Anti-RNF4 Antibody (Clone#2055CT191.101.249)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RNF4 Antibody (Clone#2055CT191.101.249) |
| 指标别名 | E3 ubiquitin ligase RNF4;Protein SNURF;RES4 26;ring finger protein 4;RNF4;SNURF |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | RNF4 |
| 克隆号 | 2055CT191.101.249 |
| 抗体来源 | Mouse |
| 免疫原 | This RNF4 antibody is generated from a mouse immunized with a recombinant protein from the human region of human RNF4. |
| 计算分子量 | 21kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | E3 ubiquitin-protein ligase which binds polysumoylated chains covalently attached to proteins and mediates 'Lys-6'-,'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitination of those substrates and their subsequent targeting to the proteasome for degradation.Regulates the degradation of several proteins including PML and the transcriptional activator PEA3.Involved in chromosome alignment and spindle assembly,it regulates the kinetochore CENPH-CENPI-CENPK complex by targeting polysumoylated CENPI to proteasomal degradation.Regulates the cellular responses to hypoxia and heat shock through degradation of respectively EPAS1 and PARP1.Alternatively,it may also bind DNA/nucleosomes and have a more direct role in the regulation of transcription for instance enhancing basal transcription and steroid receptor- mediated transcriptional activation. |
| Uniprot ID | P78317 |
相关搜索：RNF4抗体，RNF4单抗，Anti-RNF4 Antibody (Clone#2055CT191.101.249)